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Fstl1 macrophage

WebMonocytes/macrophages, a key source of IL-1β, do not normally express FSTL-1. However, FSTL-1 was found in tissue macrophages after injection of LPS into mouse footpads, demonstrating that macrophages are capable of taking up FSTL-1 at sites of inflammation. In vitro, intracellular FSTL-1 localized to the mitochondria. ... FSTL1 … WebCardiovascular diseases [ edit] FSTL1 protein seems to have a cardioprotective role. FSTL1 attenuated hypertrophy following pressure overload [17] and prevented myocardial …

Circ_0001490/miR-579-3p/FSTL1 axis modulates the survival of ...

Web联系我们 Contact Us. 电话:400-188-1050 邮箱:[email protected] WebFeb 9, 2024 · Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented. profilated meaning https://theipcshop.com

Follistatin-like protein 1 enhances NLRP3 inflammasome ... - PubMed

WebMar 21, 2024 · CircPTTG1IP knockdown suppresses rheumatoid arthritis progression by targeting miR-431-5p/FSTL1 axis. FSTL1 promotes liver fibrosis by reprogramming … WebApr 12, 2024 · Follistatin-like protein 1 (Fstl1), a glycoprotein widely expressed in human and mouse tissues, is a tumor suppressor in various cancers and a regulator in … WebExpression of inflammatory mediators, including TNF-, IL-6, and MCP-1, was significantly increased in 3T3-L1 adipocytes and RAW264.7 macrophages stimulated with recombinant FSTL1. Macrophages, a major player in obesity-induced inflammation, are recruited into adipose tissue during obesity and activated by multiple factors, including those from ... profil asp public grand est

Follistatin-like 1 in development and human diseases

Category:Circ_0001490/miR-579-3p/FSTL1 axis modulates the survival of ...

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Fstl1 macrophage

Anti-FSTL1 Antibodies Invitrogen - Thermo Fisher Scientific

WebMar 24, 2024 · The induced Fstl1 regulated inflammation response via activation of nod-like receptor family, pyrin domain containing 3v (NLRP3) inflammasome-mediated IL-1β … WebMar 29, 2024 · Follistatin-like 1 (FSTL1) is a secreted glycoprotein displaying expression changes during development and disease, among which cardiovascular disease, cancer, …

Fstl1 macrophage

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WebMar 15, 2024 · FSTL1 silencing largely overturned miR-579-3p knockdown-induced effects in M.tb-infected THP-1 macrophages. Circ_0001490 acted as miR-579-3p sponge to up-regulate FSTL1 in THP-1 macrophages. In conclusion, our results demonstrated that circ_0001490 suppressed M.tb survival and promoted the viability and inflammatory … WebJan 28, 2014 · FSTL-1 promotes caspase-1 activation in monocytes and macrophages. Human U937 cells stably transfected with plasmid encoding FSTL1 or a control plasmid were treated with LPS (200 ng/mL) or differentiated into U937 macrophages with PMA (0.5 mM). FSTL1-transfected mouse macrophage RAW264.7 cells were stimulated with or …

WebObjective: Asthma, a well-known disease with high morbidity, is characterized by chronic airway inflammation. However, the allergic inflammation mechanisms of follistatin-like … WebDec 2, 2016 · Moreover, FSTL1 downregulated expression of pro-inflammatory cytokines through suppressing MAPK/p-ERK1/2 pathway in astrocytes. Our results suggest that FSTL1 may play an anti-inflammatory role in neuroinflammation mediated by astrocytes. Follistain-like protein 1 (FSTL1), has been recently demonstrated to be involved in the …

WebJun 2, 2024 · Objective Asthma, a well-known disease with high morbidity, is characterized by chronic airway inflammation. However, the allergic inflammation mechanisms of follistatin-like protein 1 (FSTL1) have not been elucidated. This study aims to investigate the effects of FSTL1 in ovalbumin (OVA)-induced mice and macrophages on nucleotide … WebHuman FSTL1 ELISA Kit is a Sandwich (quantitative) ELISA for the measurement of Human FSTL1 in Human Cell culture supernatant, Serum, Cell ... It was suggested that fibroblast-secreted FSTL1 acts on macrophages to increase TNF and IL1B production and IL6 activity. Platform. Pre-coated microplate (12 x 8 well strips) Properties. Storage ...

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WebAug 5, 2024 · An MSC-macrophage co-culture system was constructed to further confirm the role of FSTL1 in the immunosuppressive capacity of MSCs. RNA sequencing was … profilated tipWebFeb 8, 2024 · macrophage FSTL1 in 3 murine models of liver fibrosis induced by carbon tetrachloride injection, bile duct ligation or a methionine-deficient and choline-deficient … remington l38s2WebCD51 + CD61 (Integrin alpha V + Integrin beta 3) CD51 / Integrin alpha V. CD52 profilatesWebDec 1, 2024 · FSTL1 expression was reduced in TB patients and M.tb-infected THP-1 macrophages. FSTL1 was reversely regulated by miR-579-3p in THP-1 macrophages. FSTL1 overexpression suppressed M.tb survival and elevated the viability and inflammation of THP-1 macrophages, suggesting that FSTL1 played a similar role to circ_0001490. remington l300aac1WebFollistatin-like 1 (FSTL1) functions as a pivotal modulator of inflammation and is implicated in many inflammatory diseases such as rheumatoid arthritis. Here, we report that FSTL1 is strongly upregulated and secreted during osteoclast differentiation of bone marrow-derived macrophages (BMMs) and th … remington l357m1bWeb卵泡抑素样蛋白1(follistatin-like protein 1,FSTL1)是一种分泌型细胞外基质糖蛋白,在心血管疾病、自身免疫性疾病、肿瘤、炎症等疾病模型的发生、发展和转归过程中发挥重要作用,参与多种生物学过程,包括细胞增殖、凋亡、组织分化等。FSTL1在脊椎动物神经系统中调节神经胚形成和神经元分化诱导;参 remington l9mm3bWebDec 1, 2024 · FSTL1 is reported to induce the release of macrophages- and fibroblasts-derived inflammatory cytokines [14], demonstrating that FSTL1 plays a pro-inflammatory role. Zhang et al. found that miR-32-5p facilitates the survival of M.tb pathogen and restrains the release of inflammatory factors in macrophages, and FSTL1 overexpression … profil assistant rh